Filters
Sensor Target Type Specificity Sensor Name Sensor Type Analysis Technique IV Propertiessort descending Organism Binding Protein Fluorophore PIs
Metabolites

cGMP

CGYs

FRET-based biosensors confocal flourescence microscopy CHO-K1 cells, HEK-293 cells PKG-Ia binding eCFP, eYFP Umezawa Y
Protein Activation and Conformation

Rho family GTPase activation

Raichu-RBD

FRET-based biosensors Matsuda M
Ions

Zn2+

Cys2His2

FRET-based biosensors Neurons Palmer AE
Metabolites

PtdIns(3,4,5)P3

CAY

FRET-based biosensors Swiss 3T3 fibroblasts Allen PG
Kinase Activity

Protein kinase B/Akt

Aktus

FRET-based biosensors CHO cells CFP, YFP Umezawa Y
Metabolites

PtdIns3P

GFP–p40phox iPX

Stephens LR
Ions

Ca2+

Case12/16

Single FP-based extrinsic biosensors Tsien RY, Chudakov DM, Campbell RE
Metabolites

cGMP

cGES sensors

FRET-based biosensors confocal flourescence microscopy HEK-293 cells GAF-B domain of PDE2A and GAF-A domain of PDE5A eCFP, eYFP Lohse MJ
Protein Activation and Conformation

Rho family GTPase activation

Raichu-RalA

FRET-based biosensors COS-7 cells CFP, YFP Matsuda M
Ions

Zn2+

ZapCY

FRET-based biosensors HELA cells (Cytosol, Golgi, ER) Palmer AE
Metabolites

PtdIns(3,4,5)P3

Pippi-PI(3,4,5)P3

FRET-based biosensors MDCK cells Matsuda M
Kinase Activity

Protein kinase B/Akt

Akind

FRET-based biosensors COS-7 cells CFP, YFP Matsuda M
Metabolites

PtdIns4P

GFP-PHOSH2

Translocation-based biosensors confocal microscopy Levine TP
Ions

Ca2+

Camgaroos

Single FP-based extrinsic biosensors Tsien RY, Campbell RE
Protein Activation and Conformation

Rho family GTPase activation

RhoA biosensor commentary

FRET-based biosensors Hahn KM, Hahn KM
Ions

Cd2+

Cd-FRET-2

FRET-based biosensors Merkx M
Metabolites

PtdIns(3,4,5)P3

Fllip

FRET-based biosensors CHO cells Umezawa Y
Kinase Activity

Protein kinase B/Akt

GFP-PKB-RFP

FRET-based biosensors NIH 3T3 GFP, RFP Larijani B
Metabolites

PtdIns4P

PHOSBP

Translocation-based biosensors confocal microscopy COS-7 cells GFP, mRFP Balla T, Munro S
Ions

Ca2+

B-GECO

Single FP-based extrinsic biosensors Tsien RY, Campbell RE
Protein Activation and Conformation

Wiskott -Aldrich syndrome protein (WASP) conformation

Cdc42-GEF sensors

FRET-based biosensors NIH 3T3 cells eCFP, eYFP Rosen MK
Ions

Zn2+

ZinCh

FRET-based biosensors Merkx M
Ions

Ca2+

jRCaMP1a, b

Single FP-based extrinsic biosensors Cultured neurons mRuby Kim DS
Metabolites

PtdIns(3,4,5)P3

Pippi-PI(3,4,5)P3

FRET-based biosensors COS-7 cells Matsuda M
Kinase Activity

Protein kinase B/Akt

ReAktion

FRET-based biosensors NIH 3T3 CFP, YFP Zhang J

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