Sensor Target Type![]() |
Specificity | Sensor Name | Sensor Type | Analysis Technique | IV Properties | Organism | Binding Protein | Fluorophore | PIs |
---|---|---|---|---|---|---|---|---|---|
Regulated Proteolysis |
Cell cycle progression |
Fucci |
Single FP-based extrinsic biosensors | COS-7 cells, HeLa Cells | RFP, GFP | Miyawaki A | |||
Redox and Voltage |
voltage |
SPARC |
Single FP-based extrinsic biosensors | Pieribone VA, Sakai R, Isacoff EY | |||||
Redox and Voltage |
voltage |
VSFP-cpEGFP |
FRET-based biosensors | Sakai R, Isacoff EY | |||||
Redox and Voltage |
voltage |
VSFPs |
FRET-based biosensors | Knöpfel T, Knöpfel T, Knöpfel T, Knöpfel T | |||||
Redox and Voltage |
voltage |
Mermaid |
FRET-based biosensors | Neuro2A cells | CFP, YFP | Miyawaki A | |||
Redox and Voltage |
voltage |
FlaSh-CFP/YFP |
FRET-based biosensors | salamander retinal cones, on-bipolar cells, horizontal cells, wide-field amacrine cells | eGFP, GFPuv, and wtGFP, eCFP and eYFP | Isacoff EY | |||
Redox and Voltage |
voltage |
PROPS |
Single FP-based intrinsic biosensors | E.coli | Proteorhodopsin | Cohen AE | |||
Redox and Voltage |
redox |
roGFPs |
Single FP-based intrinsic biosensors | HeLa, P388D1, or HL60 cells, HeLa and PC3 cells | roGFP | Remington SJ, Tsien RY, Remington SJ, Papa FR | |||
Redox and Voltage |
redox |
rxYFP149202 |
Single FP-based intrinsic biosensors | YFP | Winther JR | ||||
Redox and Voltage |
redox |
CY-RL5 and CY-RL7 |
FRET-based biosensors | CFP and eYFP, mCyPet and mYPet | Gaskins HR, Gaskins HR | ||||
Redox and Voltage |
redox |
HSP-FRET |
FRET-based biosensors | CFP, YFP | Schumacker PT | ||||
Redox and Voltage |
redox |
Redoxfluor |
FRET-based biosensors | CHO cells | Cerulean, Citrine | Sakai Y | |||
Redox and Voltage |
redox (H2O2) |
HyPer |
Single FP-based extrinsic biosensors | confocal microscopy | E.coli, HeLa Cells, PC12 cells | cpYFP | Lukyanov S | ||
Redox and Voltage |
redox (H2O2) |
Hyper2 |
Single FP-based extrinsic biosensors | confocal microscopy | HeLa cells, NIH 3T3 | cpYFP | Belousov VV | ||
Redox and Voltage |
redox (H2O2) |
mt-cpYFP |
Single FP-based extrinsic biosensors | confocal microscopy | human osteosarcoma cells | cpYFP | Cheng H | ||
Redox and Voltage |
redox (superoxide) |
cpYFP |
Single FP-based intrinsic biosensors | confocal microscopy | human osteosarcoma cells | cpYFP | Cheng H | ||
Redox and Voltage |
voltage |
FlaSh |
Single FP-based extrinsic biosensors | Isacoff EY, Sakai R, Isacoff EY | |||||
Redox and Voltage |
voltage |
Flare |
Single FP-based extrinsic biosensors | Sakai R, Isacoff EY | |||||
Protein Activation and Conformation |
Akt conformation |
ReAktion |
FRET-based biosensors | fluorescence microscopy | NIH3T3 fibroblasts | human Akt-1/protein kinase B-a | eCFP, Citrine | Zhang J | |
Protein Activation and Conformation |
Akt conformation |
GFP–Akt–YFP |
FRET-based biosensors | FLIM | NIH 3T3 | protein kinase B (PKB)/Akt | eGFP , eYFP | Larijani B | |
Protein Activation and Conformation |
Annexin A4 self-association |
CYNEX4 |
FRET-based biosensors | confocal flourescence microscopy, FRAP | HeLa cells, N1E-115, MDCK2 neuroblastoma cells | Annexin A4 (Ca2+ regulated phospholated) | eCFP, eYFP | Schultz C | |
Protein Activation and Conformation |
CaMKII conformation |
CamuiαamCYCaMIIα |
FRET-based biosensors | two-photon fluorescence microscopy | HeLa cells | YFP(Venus) , CFP (S175G) | Schultz C, Hayashi Y | ||
Protein Activation and Conformation |
ERK conformation |
Miu2 |
FRET-based biosensors | HeLa cells, COS-7 cells, 293F | CFP, YFP, RFP(Dropna) | Matsuda M | |||
Protein Activation and Conformation |
Estrogen receptor ligand binding domain conformation |
CEY |
FRET-based biosensors | COS-7 cells, Sf9 cells, Hf7c cells | ER-Ligand binding domain | seCFP, eYFP | Lannigan DA | ||
Protein Activation and Conformation |
G protein activation |
FP-Gα/FP-Gβ(γ) |
FRET-based biosensors | HeLa cells, HEK cells, HEK293T, Dictyostelium discoideum cells, FRT cells, haploid yeast cells | YFP(Gaq-mYFP) and CFP(mTq), YFP and CFP, eYFP | Gadella TW Jr, Lohse MJ, Bünemann M, Gilman AG, Bünemann M, Devreotes P, Scarlata S, Simon MI |