Biosensor | DPB/DGE Codex

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Sensor Target Type	Specificity	Sensor Name	Sensor Type	Analysis Technique	Organism	Fluorophore	PIs
Regulated Proteolysis	Cell cycle progression	Fucci	Single FP-based extrinsic biosensors		COS-7 cells, HeLa Cells	RFP, GFP	Miyawaki A
Redox and Voltage	redox	roGFPs	Single FP-based intrinsic biosensors		HeLa, P388D1, or HL60 cells, HeLa and PC3 cells	roGFP	Remington SJ, Tsien RY, Remington SJ, Papa FR
Redox and Voltage	redox	rxYFP¹⁴⁹₂₀₂	Single FP-based intrinsic biosensors			YFP	Winther JR
Redox and Voltage	redox	CY-RL5 and CY-RL7	FRET-based biosensors			CFP and eYFP, mCyPet and mYPet	Gaskins HR, Gaskins HR
Redox and Voltage	redox	HSP-FRET	FRET-based biosensors			CFP, YFP	Schumacker PT
Redox and Voltage	redox	Redoxfluor	FRET-based biosensors		CHO cells	Cerulean, Citrine	Sakai Y
Redox and Voltage	redox (H₂O₂)	HyPer	Single FP-based extrinsic biosensors	confocal microscopy	E.coli, HeLa Cells, PC12 cells	cpYFP	Lukyanov S
Redox and Voltage	redox (H₂O₂)	Hyper2	Single FP-based extrinsic biosensors	confocal microscopy	HeLa cells, NIH 3T3	cpYFP	Belousov VV
Redox and Voltage	redox (H₂O₂)	mt-cpYFP	Single FP-based extrinsic biosensors	confocal microscopy	human osteosarcoma cells	cpYFP	Cheng H
Redox and Voltage	redox (superoxide)	cpYFP	Single FP-based intrinsic biosensors	confocal microscopy	human osteosarcoma cells	cpYFP	Cheng H
Redox and Voltage	voltage	FlaSh	Single FP-based extrinsic biosensors				Isacoff EY, Sakai R, Isacoff EY
Redox and Voltage	voltage	Flare	Single FP-based extrinsic biosensors				Sakai R, Isacoff EY
Redox and Voltage	voltage	SPARC	Single FP-based extrinsic biosensors				Pieribone VA, Sakai R, Isacoff EY
Redox and Voltage	voltage	VSFP-cpEGFP	FRET-based biosensors				Sakai R, Isacoff EY
Redox and Voltage	voltage	VSFPs	FRET-based biosensors				Knöpfel T, Knöpfel T, Knöpfel T, Knöpfel T
Redox and Voltage	voltage	Mermaid	FRET-based biosensors		Neuro2A cells	CFP, YFP	Miyawaki A
Redox and Voltage	voltage	FlaSh-CFP/YFP	FRET-based biosensors		salamander retinal cones, on-bipolar cells, horizontal cells, wide-field amacrine cells	eGFP, GFPuv, and wtGFP, eCFP and eYFP	Isacoff EY
Redox and Voltage	voltage	PROPS	Single FP-based intrinsic biosensors		E.coli	Proteorhodopsin	Cohen AE
Protein Activation and Conformation	M(1) muscarinic receptor (M(1)R) activation	M₁R-YFP-CFP	FRET-based biosensors	fluorescence microscopy	tsA-201 cells	eCFP, eYFP	Hille B
Protein Activation and Conformation	MAP kinase-activated protein kinase 2 conformation	GMB	FRET-based biosensors		HEK293 cells, Swiss 3T3 cells	eCFP, eBFP	Gaestel M
Protein Activation and Conformation	PKB conformation	GFP-PKB-RFP	FRET-based biosensors		NIH 3T3	eGFP , RFP	Larijani B
Protein Activation and Conformation	Rho family GTPase activation	Raichu-Rap1	FRET-based biosensors				Matsuda M, Matsuda M
Protein Activation and Conformation	Rho family GTPase activation	Raichu-Rap1	FRET-based biosensors				Matsuda M, Matsuda M
Protein Activation and Conformation	Rho family GTPase activation	Raichu-Rac	FRET-based biosensors		COS-1 cells, HEK293 cells, 293T cells, HT1080 cells, HeLa cells	CFP and YFP	Matsuda M, Matsuda M
Protein Activation and Conformation	Rho family GTPase activation	Raichu-Cdc42	FRET-based biosensors				Matsuda M, Matsuda M

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